![]() ![]() OHSU fertility experts can offer options before your treatment begins to preserve your ability to have children. A stem cell transplant allows you to be treated with a higher dose of chemotherapy than you would usually be able to have because it replaces the stem cells. Infertility: The chemotherapy and radiation therapy used before transplants typically result in infertility. We’ll monitor you closely for signs of any problem. Stem cell transplant techniques are continually changing, so consider asking your doctors for more details about sources of stem cells. Organ damage: Chemotherapy and radiation can leave lasting damage. This common complication can range from mild to life-threatening. Graft-versus-host disease: This happens when transplanted cells from the donor attack the recipient’s tissue and organs. This is rare with stem cell transplants but more common when HLA types are poorly matched. ![]() Graft failure: Transplant (graft) failure occurs when the body rejects the donor cells. It may cause difficulty eating or swallowing for a few weeks. Pain: Mouth or throat pain is a common side effect of chemotherapy and radiation therapy. Some patients may need a blood transfusion to replace platelets. We will take great care to help you avoid injury or bleeding. Low platelets: Your platelets will be low for three or more weeks. You will receive safety instructions for going home. Your care team will keep you in a safe environment with protection against airborne germs. You are at high risk of infection for up to six weeks until your new cells make healthy blood cells. ![]() Infection: Chemotherapy and radiation therapy weaken your immune system. Before SCT, the patient receives high doses of chemotherapy, and sometimes radiation therapy, to prepare the body for transplantation. Your care team will discuss these with you in detail. Stem cell transplantation (SCT), sometimes referred to as bone marrow transplant, is a procedure in which a patient receives healthy stem cells to replace damaged stem cells. The service has a very strong track record in translational research and an on-going commitment to pioneering new therapies and participating in both national and international trials.As with any procedure, transplants involve risks. The HSCT service at UCLH has strong links with University College London (UCL). Patient aftercareĪll patients undergoing transplant at UCLH are closely followed up following their procedure.įor autologous transplant patients, you will be followed up at UCLH for approximately three months and referred back to your referring centre.įor allogeneic transplant patients, your post-transplant care will be delivered almost exclusively by UCLH and you will remain in frequent contact with the service. This will be dependent upon the type of transplant you are having, and will be discussed with you as your transplant is being planned. Your treatment may take place as an outpatient in an ambulatory setting (without the need for an overnight stay in hospital, but in nearby accommodation) at University College London Hospital Macmillan Cancer Centre, or in the main hospital building - University College Hospital. The transplant team will decide whether you are suitable for transplant treatment. If you are having this type of transplant, a transplant clinical nurse specialist (CNS) will become your permanent 'key worker’. This involves taking healthy stem cells from the blood or bone marrow of one person – either a family member or an unrelated donor – and transferring them to another person. You will have a new clinical nurse specialist (CNS) who will coordinate this and who will be your 'key worker', but you will return to your original CNS - three months after your transplant. This involves removing stem cells from your own body and transplanting them later, after any damaged or diseased cells have been removed. Out-of-hours: Haematology specialist registrar via UCLH switchboard, 020 3456 7890. Stem cell and bone marrow transplants (BMT) ![]()
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